Search results for "paracrine factors"

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Identification of Specific Somatic Stem Cell Markers in the Human Endometrium and Mechanisms of the Bone Marrow for Endometrial Regeneration

2018

INTRODUCTION The endometrium is a unique tissue with a high reconstitution potential during the menstrual cycle throughout the women’s reproductive life. This high regenerative potential seems to be due to the presence of somatic stem cells (SSCs) residing in the endometrial niche inside this tissue. Apart from this endogenous source, an exogenous source of stem cells composed by bone marrow-derived stem cells (BMDSCs) is postulated to exist. The endometrial contribution of bone marrow has been described in healthy and diseased women. Specifically, transplanted BMDSCs release soluble factors under tissue damage that contribute to tissue repair. To be able to differentiate both populations o…

W5C5Stem cell markersStem cells:CIENCIAS MÉDICAS [UNESCO]:CIENCIAS DE LA VIDA [UNESCO]ICAM1EndometriumUNESCO::CIENCIAS DE LA VIDA::Fisiología humana ::Fisiología de la reproducción:CIENCIAS DE LA VIDA::Fisiología humana ::Fisiología de la reproducción [UNESCO]NicheSide PopulationUNESCO::CIENCIAS MÉDICASUNESCO::CIENCIAS DE LA VIDAParacrine FactorsReproductive medicine
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Mesenchymal Stem Cells Provide Better Results Than Hematopoietic Precursors for the Treatment of Myocardial Infarction

2010

Objectives The purpose of this study was to compare the ability of human CD34(+) hematopoietic stem cells and bone marrow mesenchymal stem cells (MSC) to treat myocardial infarction (MI) in a model of permanent left descendent coronary artery (LDA) ligation in nude rats. Background Transplantation of human CD34(+) cells and MSC has been proved to be effective in treating MI, but no comparative studies have been performed to elucidate which treatment prevents left ventricular (LV) remodelling more efficiently. Methods Human bone marrow MSC or freshly isolated CD34(+) cells from umbilical cord blood were injected intramyocardially in infarcted nude rats. Cardiac function was analyzed by echoc…

mesenchymal stem cellsPathologymedicine.medical_specialtybusiness.industrymedicine.medical_treatmentMesenchymal stem cellCD34hematopoietic precursorsHematopoietic stem cell transplantationmedicine.diseaseTransplantationleft ventricular functionHaematopoiesismyocardial infarctionmedicine.anatomical_structureImmunologymedicineMyocardial infarctionparacrine factorsStem cellCardiology and Cardiovascular MedicinebusinessArteryJournal of the American College of Cardiology
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